Last edited by Netaur
Monday, July 13, 2020 | History

6 edition of Post-Transcriptional Control of NMDA Receptor Expression (Special Issue Neurosignals 2004) found in the catalog.

Post-Transcriptional Control of NMDA Receptor Expression (Special Issue Neurosignals 2004)

by Nikolaus J Sucher

  • 251 Want to read
  • 34 Currently reading

Published by Karger .
Written in English

    Subjects:
  • Neurology & clinical neurophysiology,
  • Neurology - General,
  • Medical

  • The Physical Object
    FormatPaperback
    Number of Pages50
    ID Numbers
    Open LibraryOL12931680M
    ISBN 103805577710
    ISBN 109783805577717

    Molecular Pathways of Down Syndrome Critical Region Genes. By Ferdinando Di Cunto and Gaia Berto. Submitted: (NMDA) receptor Indeed many of these sequences have been implicated in the epigenetic and in the post-transcriptional control of gene expression. Moreover, since these sequences diverge much more rapidly than the sequences of Cited by: 3. Post-transcriptional regulatory mechanisms have emerged as a critical component underlying the diversification and spatiotemporal control of the proteome during the establishment of precise neuronal connectivity. These mechanisms have been shown to be important for virtually all stages of assembling a neural network, from neurite guidance.

    “Effects of NMDA receptor modulators on network activity in a human iPSC-derived model of cortical dysfunction in Rett Syndrome” ), it has been accepted that shared book reading is an effective approach to communication and emergent literacy intervention for children with RTT. “Post-transcriptional control of MECP2 expression. Since the guiding principles of Replace, Reduce, and Refine were published, wider context-of-use for alternatives to animal testing have emerged. Induced pluripotent stem cell-derived human glutamatergic-enriched cortical neurons can be leveraged as 2- and 3-dimensional platforms to enable candidate drug screening. Uniquely so, 2-dimensional models are useful considering that they exhibit Author: Yafei Chen.

    Enhanced zif expression by serum- and glucocorticoid-inducible kinase 1 through the mediation of SRF and CREB1 and its association with spatial memory formation Advisor: Eminy H. Y. Lee, Ph.D., Academic Sinica, Taipei, Taiwan Histological analysis of hippocampus-specific NMDA receptor subunit 1 NR mutant mice Ethanol attenuates NMDA receptor function in a dose-related fashion in vitro [42,43]. The NMDA receptor is a heteromeric protein composed of at least one NR1 subunit and at least one NR2 subunit. Ethanol appears to bind to the NR1 subunit in a hydrophobic pocket associated with Cited by:


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Post-Transcriptional Control of NMDA Receptor Expression (Special Issue Neurosignals 2004) by Nikolaus J Sucher Download PDF EPUB FB2

Note: Citations are based on reference standards. However, formatting rules can vary widely between applications and fields of interest or study. The specific requirements or preferences of your reviewing publisher, classroom teacher, institution or organization should be applied.

NMDA receptor expression Post-transcriptional control of N-methyl-D-aspartate receptor expression N-methyl-D-aspartate receptor expression Neuro-Signals. Responsibility: guest editor, Nikolaus J.

Sucher. Expression of endogenous NMDAR1 transcripts without receptor protein suggests post-transcriptional control in PC12 cells Article (PDF Available) in Journal of Biological Chemistry (30) Chapter 6 NMDA Receptors and Translational Control.

Peleg D, Meyuhas O. Selective translational control and nonspecific post-transcriptional regulation of ribosomal protein gene expression during development and regeneration of rat liver. Contribution of NMDA receptor channels to the expression of LTP in the hippocampal dentate gyrus Cited by: 7.

THE JOURNAL OF BIOLOGICAL CHEMISTRY 0 by The American Society fox Biochemistry and Moleeular Biology, Inc. Vol.No. 30, Issue of October 25, pp. Printed in d.S.A. Expression of Endogenous NMDAR1 Transcripts without Receptor Protein Suggests Post-transcriptional Control in PC12 Cells* (Received for publication, June 7, ).

Glutamate Receptors: NMDA and Delta Receptors has been suggested to control NMDA receptor gating, leading to the hypothesis that the proton sensor and receptor gate may be structurally and. Oct 24,  · At the post-transcriptional level, intracellular calcium level changes can change alternative splicing patterns; in the mammalian brain, alterations in calcium signaling via NMDA receptors is associated with exon silencing of the CI cassette of the NMDA R1 receptor (GRIN1) transcript by UAGG motifs in response to neuronal excitation.

Regulation Author: Basant K. Puri. The mammalian target of rapamycin (mTOR), a serine/threonine kinase, is a therapeutic target for many types of cancers.

NMDA receptors regulate mTOR signalling activity; their inappropriate expression on several human cancer cell lines represents a potential therapeutic avenue to control dysregulated growth, division and lapachecachica.com by: Both transcriptional and post-transcriptional mechanisms control GAP gene expression during development.

While promoter activity determines the neural-specific expression of the gene, changes in mRNA stability modulate GAP expression in neurons undergoing process outgrowth in response to growth factors and other signaling lapachecachica.com: Nora Perrone-Bizzozero, Rebecca Keller.

Lack of functional expression of NMDA receptors in PC12 cells. but may be due to post-transcriptional control induced by different culturing conditions from laboratory to laboratory. In the absence of functional NMDA receptor expression, the mechanism by which NMDA or glutamate induces excitotoxicity in any given PC12 cell line cannot Cited by: The α-aminohydroxymethylisoxazolepropionic acid receptor (also known as AMPA receptor, AMPAR, or quisqualate receptor) is an ionotropic transmembrane receptor for glutamate that mediates fast synaptic transmission in the central nervous system (CNS).

It has been traditionally classified as a non-NMDA-type receptor, along with the kainate receptor. Reflecting the rapid progress in the field, the book presents the current understanding of molecular mechanisms of post-transcriptional gene regulation thereby focusing on RNA processing mechanisms in eucaryotic cells.

With chapters on mechanisms as RNA splicing, RNA interference, MicroRNAs, RNA editing and others, the book also discusses the critical role of RNA processing for the. Information storage in the brain involves alterations in the strength of communication between neurons.

This requires activity-dependent, long-lasting changes in synaptic transmission. Long-term potentiation (LTP) is a long lasting use-dependent increase in the efficiency of excitatory synaptic transmission that has been suggested to underlie certain forms of learning and memory [1].

The Author: Sophie Restituito, Edward B. Ziff. Jul 15,  · In order to determine the exact post-transcriptional control of IGF1Rby SEVO, we did a miRNA assay on 5% SEVO-treated HCN-2 cells versus control cells and highlighted IGF1R-binding miRNAs (Fig.

3A). We found that among these IGF1R-binding miRNAs, only miRp significantly increased after exposure to 5% SEVO (Fig. 3B).Author: Yuan Tian, Mingrui Song. Edition, Post-Transcriptional Control of Nmda Receptor Expression, Control & Dynamic Systems, Volume Stochastic Digital Control System Techniques, National Cancer Control Programmes, Sistemas de Control de Cambios En Chile, Documentation of research and studies on social.

The ligand-receptor complex moves into the nucleus, then binds to specific regions of the DNA and promotes the production of mRNA from specific genes (Figure 2). Internal receptors can directly influence gene expression (how much of a specific protein is produced from a gene) without having to pass the signal on to other receptors or lapachecachica.com: Lisa Bartee, Walter Shriner, Catherine Creech.

In addition, miR/ cluster is actively repressing the expression of mu opioid receptor by targeting a sequence in the 3’ UTR of its mRNA. These findings suggest that this cluster is closely related to opioid signaling, and function as a post-transcriptional regulator, modulating morphine response in a dose dependent lapachecachica.com by: 7.

Andrea C Gore Professor College of Roberts JL () The role of calcium in the transcriptional and post-transcriptional regulation of the gonadotropin-releasing hormone gene in GT cells.

Endocrinology NMDA receptor subunit expression in gonadotropin-releasing hormone neurons changes during reproductive senescence in. Oct 14,  · Abstract. The N-methyl-d-aspartate (NMDA) type of glutamate receptor (NMDAR) plays central roles in normal and pathological neuronal lapachecachica.com have examined the regulation of the NR1 subunit of the NMDAR in response to excessive activation of this receptor in in vitro and in vivo models of excitotoxicity.

NR1 protein expression in cultured cortical neurons was specifically reduced Author: Sergio Gascón. Inducing experimental autoimmune encephalomyelitis in animals as a model for multiple sclerosis(MS) has targeted some glutamate receptors as a pathway for potential therapeutic applications; this research has found that a group of drugs interact with the NMDA, AMPA, and kainate glutamate receptor to control neurovascular permeability.

The α-aminohydroxymethylisoxazolepropionic acid receptor (also known as AMPA receptor, AMPAR, or quisqualate receptor) is an ionotropic transmembrane receptor for glutamate that mediates fast synaptic transmission in the central nervous system (CNS).

It has been traditionally classified as a non-NMDA-type receptor, along with the kainate receptor, its name is derived from its ability.The Molecular Neurobiology of Twelve Steps Program & Fellowship: Connecting the Dots for Recovery expression of the NMDA receptor 2B (NR2B) gene is upregulated following chronic intermittent ethanol (CIE) treatment and withdrawal.

Agan G, Fratantonio J, Simpatico T, et al. The Molecular Neurobiology of Twelve Steps Program.In the present study, we investigated the effects of BPA (ranging from 1 to nM), focusing on the rapid dynamic changes in dendritic filopodia and the expressions of estrogen receptor (ER) {beta} and NMDA receptor, as well as the phosphorylation of NMDA receptor subunit NR2B in the cultured hippocampal neurons.